cikakkun matakai game da yadda ake amfani da microspheres embolic

Microspheres na Embolic microspheres ne masu matsawa waɗanda ke da siffa ta yau da kullun, saman da yake santsi, da girman da aka daidaita, waɗanda aka samar sakamakon gyaran sinadarai akan kayan polyvinyl alcohol (PVA). Microspheres na Embolic sun ƙunshi macromer da aka samo daga polyvinyl alcohol (PVA), kuma suna da hydrophilic, ba za a iya sake shafawa ba, kuma suna samuwa a cikin girma dabam-dabam. Maganin kiyayewa shine maganin sodium chloride 0.9%. Yawan ruwan microsphere da aka polymerized cikakke shine 91% ~ 94%. Microspheres na iya jure matsin lamba na 30%.

An yi nufin amfani da ƙananan ƙwayoyin halittar jini (Embolic Microspheres) don embolization na jijiyoyin jini (AVMs) da ciwon daji masu yawan jini, gami da fibroids na mahaifa. Ta hanyar toshe hanyoyin jini zuwa yankin da ake nufi, ciwon ko matsalar na iya zama rashin abinci mai gina jiki kuma girmansa yana raguwa.

A cikin wannan labarin, za mu nuna muku cikakkun matakai game da yadda ake amfani da Embolic Microspheres.

Shirye-shiryen kaya

Ya zama dole a shirya sirinji 1 mai nauyin 20ml, sirinji 2 mai nauyin 10ml, sirinji 3 mai nauyin 1ml ko 2ml, almakashi mai amfani da hanyoyin uku, ƙoƙon tiyata mai tsafta, magungunan chemotherapy, microspheres masu kama da juna, maganin contrast, da ruwa don allura.

Mataki na 1: Saita magungunan chemotherapy

Yi amfani da almakashi na tiyata don buɗe kwalbar maganin chemotherapy sannan a zuba maganin chemotherapy a cikin kofi mara tsafta.
Nau'in da kuma yawan magungunan chemotherapy sun dogara ne akan buƙatun asibiti.

Yi amfani da ruwa don allura don narkar da magungunan chemotherapy, kuma yawan da aka ba da shawarar shine fiye da 20mg/ml.

ABayan maganin chemotherapy ya narke gaba ɗaya, an cire maganin chemotherapy da sirinji 10ml.

Mataki na 2: Cire ƙwayoyin cuta masu ɗauke da ƙwayoyin cuta masu kama da embolic

An girgiza ƙananan ƙwayoyin halittar da aka ƙera gaba ɗaya, an saka su cikin allurar sirinji don daidaita matsin lamba a cikin kwalbar,sannan a cire ruwan da microspheres daga kwalbar cillin da sirinji 20ml.

A bar sirinji ya tsaya na tsawon mintuna 2-3, kuma bayan microspheres sun lafa, sai a fitar da ruwan da ke cikin ruwan.

Mataki na 3: Sanya magungunan Chemotherapeutic a cikin Embolic Microspheres

Yi amfani da hanyar stopcock guda 3 don haɗa sirinji da microsphere na embolic da sirinji tare da maganin chemotherapy, kula da haɗin gwiwa da kyau da kuma alkiblar kwarara.
A tura sirinji na maganin chemotherapy da hannu ɗaya, sannan a ja sirinji mai ɗauke da ƙwayoyin cuta masu kama da embolic da ɗayan hannun. A ƙarshe, ana haɗa maganin chemotherapy da ƙwayoyin cuta masu kama da microsphere a cikin sirinji na 20ml, a girgiza sirinji sosai, sannan a bar shi na tsawon minti 30, a girgiza shi bayan kowane minti 5 a lokacin al'ada.

Mataki na 4: Ƙara kafofin watsa labarai masu bambanci

Bayan an ɗora magungunan chemotherapeutic na tsawon mintuna 30, an ƙididdige yawan maganin.
Sai a zuba sau 1-1.2 na ruwan maganin contrast a cikin ruwan maganin ta hanyar amfani da hanyar three ways stopcock, a girgiza sosai sannan a bar shi ya tsaya na tsawon minti 5.

Mataki na 5: Ana amfani da ƙananan ƙwayoyin cuta a cikin tsarin TACE

Ta hanyar bututun dakatarwa mai hanyoyi uku, a yi allurar kusan 1ml na microspheres a cikin sirinji na 1ml.

An yi allurar microspheres a cikin microcatheter ta hanyar allurar da aka yi ta bugun jini.

Jagorar hankali:

Don Allah a tabbatar an yi aikin maganin septic.
Tabbatar cewa magungunan chemotherapy sun narke gaba ɗaya kafin a ɗora su a kan maganin.
Yawan magungunan chemotherapy zai shafi tasirin lodin magani, mafi girman yawan da ake samu, saurin sha, yawan da ake buƙata na ɗaukar magani bai kai ƙasa da 20mg/ml ba.
Ya kamata a yi amfani da ruwan da ba a tsaftace ba kawai don allura ko kuma allurar glucose 5% don narkar da magungunan chemotherapy.
Yawan narkewar doxorubicin a cikin ruwan da ba a tsaftace ba don allura ya ɗan fi sauri fiye da kashi 5% na allurar glucose.
Allurar glucose kashi 5% tana narkar da pirabuciin da sauri fiye da ruwan da aka yi amfani da shi wajen allura.
Amfani da ioformol 350 a matsayin hanyar kwatantawa ya fi dacewa da dakatar da ƙwayoyin microspheres.
Idan aka yi allurar a cikin ƙari ta hanyar microcatheter, ana amfani da allurar bugun zuciya, wanda ya fi dacewa da dakatarwar microsphere.