Embolic Microspheres sune microspheres hydrogel masu matsawa tare da siffa ta yau da kullun, daɗaɗaɗɗen wuri, da girman calibrated, waɗanda aka samo su sakamakon gyare-gyaren sinadarai akan kayan polyvinyl barasa (PVA).Embolic Microspheres sun ƙunshi macromer da aka samo daga polyvinyl barasa (PVA), kuma suna da hydrophilic, ba za a iya sake sakewa ba, kuma suna samuwa a cikin kewayon masu girma dabam.Maganin adanawa shine 0.9% maganin sodium chloride.Abubuwan da ke cikin ruwa na cikakken microsphere polymerized shine 91% ~ 94%.Microspheres na iya jure wa matsawa na 30%.
An yi nufin amfani da Microspheres na Embolic don ƙaddamar da ƙwayoyin cuta na arteriovenous (AVMs) da kuma ciwon hawan jini, ciki har da fibroids na mahaifa.Ta hanyar toshe isar da jini zuwa yankin da aka yi niyya, ƙwayar cuta ko rashin lafiya yana fama da yunwar abubuwan gina jiki kuma yana raguwa cikin girma.
A cikin wannan labarin, za mu nuna muku cikakken matakai game da yadda ake amfani da Embolic Microspheres.
Shirye-shiryen kaya
Wajibi ne a shirya sirinji 1 20ml, 2 10ml sirinji, 3 1ml ko 2ml sirinji, hanyoyi uku, almakashi na tiyata, kofin bakararre, magungunan chemotherapy, microspheres embolic, kafofin watsa labaru, da ruwa don allura.
Mataki 1: Sanya magungunan chemotherapy
Yi amfani da almakashi na fiɗa don kwance kwalaben magani na chemotherapeutic da kuma zuba maganin chemotherapeutic a cikin kofi mara kyau.
Nau'in da adadin magungunan chemotherapeutic ya dogara da bukatun asibiti.
Yi amfani da ruwa don allura don narkar da magungunan chemotherapy, kuma shawarar da aka ba da shawarar ya fi 20mg/ml.
Abayan an gama narkar da maganin cutar sankarau, an fitar da maganin maganin kashe kwayoyin cuta tare da sirinji 10ml.
Mataki na 2: Cire ƙananan ƙwayoyin cuta masu ɗauke da ƙwayoyi
An girgiza microspheres da aka ruɗe, an saka su a cikin allurar sirinji don daidaita matsa lamba a cikin kwalbar,kuma cire maganin da microspheres daga kwalban cillin tare da sirinji 20ml.
Bari sirinji ya tsaya na minti 2-3, kuma bayan microspheres sun daidaita, an fitar da supernatant daga maganin.
Mataki 3: Load da Chemotherapeutic kwayoyi cikin Embolic Microspheres
Yi amfani da 3 hanyoyi na tsayawa don haɗa sirinji tare da microsphere embolic da sirinji tare da maganin chemotherapy, kula da haɗin gwiwa da ƙarfi da hanyar gudana.
Tura sirinji na maganin chemotherapy da hannu ɗaya, sannan ka ja sirinji mai ɗauke da ƙananan ƙwayoyin cuta da ɗaya hannun.A ƙarshe, ana haɗa maganin chemotherapy da microsphere a cikin sirinji na 20ml, girgiza sirinji da kyau, sannan a bar shi na mintuna 30, girgiza shi kowane minti 5 yayin lokacin.
Mataki na 4: Ƙara kafofin watsa labarai masu bambanci
Bayan an ɗora microspheres tare da magungunan chemotherapeutic na minti 30, an ƙididdige ƙarar maganin.
Ƙara sau 1-1.2 ƙarar wakili mai bambanci ta hanyar katako mai tsayi uku, girgiza da kyau kuma bari ya tsaya na minti 5.
Mataki 5: Ana amfani da Microspheres a cikin tsarin TACE
Ta hanyar cockcock guda uku, allura kusan 1ml na microspheres a cikin sirinji 1ml.
An yi wa ƙananan ƙwayoyin cuta a cikin microcatheter ta hanyar allurar bugun jini.
Jagorar hankali:
Da fatan za a tabbatar da aikin aseptic.
Tabbatar cewa magungunan chemotherapeutic sun narkar da gaba ɗaya kafin loda magungunan.
Ƙaddamar da magungunan ƙwayoyin cuta za su shafi tasirin maganin miyagun ƙwayoyi, mafi girman ƙaddamarwa, da sauri da adadin adsorption, ƙaddamar da ƙaddamarwa na miyagun ƙwayoyi ba kasa da 20mg / ml ba.
Ruwan da bakararre kawai don allura ko allurar glucose 5% yakamata a yi amfani dashi don narkar da magungunan chemotherapy.
Adadin narkar da doxorubicin a cikin ruwa mara kyau don allura ya ɗan yi sauri fiye da 5% na allurar glucose.
5% allurar glucose tana narkar da pirarubicin da sauri fiye da bakararre ruwa don allura.
Yin amfani da ioformol 350 a matsayin matsakaicin matsakaici ya fi dacewa da dakatar da microspheres.
Lokacin yin allurar cikin ƙwayar cuta ta hanyar microcatheter, ana amfani da allurar bugun jini, wanda ya fi dacewa da dakatarwar microsphere.
Lokacin aikawa: Fabrairu-28-2024